As well as being addictive, drinking too much of the Brew will cause serious illness to the consumer. It has also been know to make the drinker fart explosively afterwards. This is particularly noticeable with Abe, as it has the strange side-effect of turning Abe's farts into explosive 'air-bombs' that can be possessed.
Somehow, Abe was not addicted or made sick by the Brew and managed to rescue the sick and enslaved Mudokons, and eventually succeeded in blowing up the SoulStorm Brewery (it is possible that the brew sickness healing power that the Three Weirdos gave him also granted him immunity to brew sickness and the addictive parts of SoulStorm Brew). The brew has since ceased production, however when Munch was seen in the poop chute in Vykker's Labs, on top of several crates where (presumably) empty bottles of SoulStorm brew most likely purchased before the brewery was destroyed.
- In Abe's Exoddus, Abe's friends chug down all ninety-nine bottles of SoulStorm Brew. This is a reference to the song, 99 Bottles of Beer on the Wall.